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These changes were not accompanied by significant changes in disease activity and health-related quality of life
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Research shows that both moderate-intensity continuous training (MICT, 50%–70% VO 2 max) and high-intensity interval training (HIIT, 85%–95% VO 2 max) can effectively activate the Nrf2 pathway, with HIIT being 30%–40% more effective in upregulating antioxidant enzymes than MICT (Martinez-Canton et al., 2024)
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